Hello. My wife one year ago discovered hepatitis B. Results from the analysis: DNA virus HepB. B-discovered (5 +) 1:10000 anti-HAV IgG + HBsAg + anti-HBs - anti-HBc sumarnye + anti-HBc IgM - HBeAg + anti-HBe - anti-HCV IgM - anti-HDV IgM - ALT 50 AST 36 doctors appointed a course of treatment: as a result during the year were conducted courses of treatment with: Pegasys PegIntron zeffiks alfaferon realdiron After each course, indicators of DNA are not changed. The organism does not respond to therapy, injections carried nezamentno. Please tell me know if you are such cases? How can this be explained? And explain what immunotolerantny hepatitis B? Please reply! I love her so much and worried for her. Vzaranee thanks!

Respond Stanislav Y. Karpov, hepatology, gastroenterology, hepatology and gastroenterology clinic Medal Hepatitis B is difficult to treat. The effectiveness of antiviral therapy of hepatitis B does not exceed 25%. Treatment for those infected with hepatitis B virus was shown only in the case of active virus (10 * 5 copies / ml or more) and elevated levels of ALT and / or ACT. Come to see a doctor in our clinic to discuss further action. My days of reception - Friday and Sunday. Similar question: ... drink. Here are the results of tests: HBsAg (-), anti-HCV (-), anti-HBs (+), anti-HBc IgG (+), HBV DNA B (-), ALT (59) and AST (53) were discharged gepamerts ...